Your pharmacist can provide more information about acyclovir. Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. The vast majority of otherwise healthy people who get H1N1 swine flu pull through just fine, after a few miserable days of flu symptoms. serevent
April 2009 and never went away. What happens if I miss a dose Zovirax? Nausea and vomiting are more frequent in elderly subjects. Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Acyclovir will not treat a viral infection such as the common cold or flu. Talk with family members and loved ones about how they would be cared for if they got sick, or what will be needed to care for them in your home.
Products meeting necessary bioequivalence requirements. By midsummer 2010, there was only a trickle of H1N1 infections, but deaths and hospitalizations continued among at-risk people who had not been vaccinated. Genital herpes can also be transmitted in the absence of symptoms through asymptomatic viral shedding. If medical management of a genital herpes recurrence is indicated, patients should be advised to initiate therapy at the first sign or symptom of an episode.
HUS which has resulted in death, has occurred in immunocompromised patients receiving acyclovir therapy. Warm baths and numbing cream may relieve the pain associated with genital sores. Some people who may have had seasonal H1N1 flu before 1957 might have a little bit of protective immunity against the new virus. That's because seasonal H1N1 flu strains that circulated before 1957 and which were replaced by the 1957 pandemic flu bug were genetically closer to the 2009 H1N1 swine flu. This protection is not complete. While relatively few elderly people have had H1N1 swine flu, many of those who did get the disease became severely ill. What are swine flu symptoms?
Do not take this medicine if you are allergic to acyclovir or valacyclovir Valtrex. Use this medication regularly to get the most benefit from it. This medication works best when the amount of drug absorbed by the skin stays at a constant level. Therefore, use this drug at evenly spaced intervals. To help you remember, use it at the same times each day. This medication is given by slow injection into a vein as directed by your doctor. It is usually given every 8 hours. It should be injected slowly over 1 hour. Do not inject rapidly. Start this medication as soon as signs or symptoms of a herpes infection occur. Dosage is based on your medical condition, weight, and response to treatment. OTC remedies, but getting too much can be dangerous. If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. It causes red, scaly, waxy patches that eventually go away without treatment. You might notice it on other parts of your baby's body, too. Apply sufficient quantity to adequately cover all lesions every 3 hours, 6 times per day for 7 days. The dose size per application will vary depending upon the total lesion area but should approximate a one-half inch ribbon of ointment per 4 square inches of surface area. A finger cot or rubber glove should be used when applying ZOVIRAX to prevent autoinoculation of other body sites and transmission of infection to other persons. Therapy should be initiated as early as possible following onset of signs and symptoms. The CDC advises against the use of the anti-flu drugs and Relenza to keep exposed people from getting the flu. That's because most of the few cases of drug-resistant H1N1 swine flu have popped up in people taking Tamiflu to prevent flu. Dr. Richard Pazdur, director of the Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research, said in the news release. Severe local inflammatory reactions, including tissue necrosis, have occurred following infusion into extravascular tissues. Application site pain and application site irritation have occurred with the buccal tablets. People who have or are suspected of having swine flu should wear a face mask, if available and tolerable, when sharing common spaces with other household members, when outside the home, or when near children or infants. If you are using the liquid form of this medication, shake the bottle well before each dose. The inhibitory activity of acyclovir is highly selective due to its affinity for the enzyme thymidine kinase TK encoded by HSV and VZV. This viral enzyme converts acyclovir into acyclovir monophosphate, a nucleotide analogue. The monophosphate is further converted into diphosphate by cellular guanylate kinase and into triphosphate by a number of cellular enzymes. In vitro, acyclovir triphosphate stops replication of herpes viral DNA. This is accomplished in 3 ways: 1 competitive inhibition of viral DNA polymerase, 2 incorporation into and termination of the growing viral DNA chain, and 3 inactivation of the viral DNA polymerase.
Geriatrics: Acyclovir plasma concentrations are higher in geriatric patients compared with younger adults, in part due to age-related changes in renal function. Dosage reduction may be required in geriatric patients with underlying renal impairment see PRECAUTIONS: Geriatric Use. Spurred by the safety concerns that sank vaccination efforts during the 1976 swine flu scare a scare caused by a very different generation of flu vaccine against a very different swine flu virus federal officials have increased efforts to track the safety of the H1N1 swine flu vaccine. Skip the creams you find in the drug store unless your doctor tells you to use one. They can irritate your baby's bottom even more if used incorrectly. HSV-1 or and type 2 HSV-2 or . Most commonly, HSV-1 causes sores sometimes called "" or "" around the and lips. How serious is the public health threat of a swine flu epidemic? Tell your doctor if your condition persists or worsens. Food and Drug Administration. WebMD does not endorse any specific product, service or treatment. IC50 vary greatly depending upon a number of factors. In a word: no. It's not always possible to know with complete certainty when an STD like herpes is transmissible. That's because herpes can "shed" the virus and spread even when there is no sign of an active herpes outbreak. And such "asymptomatic shedding" does occur, explaining how herpes is transmitted to so many unsuspecting people. If you do get medication in those areas, flush with plenty of water. Use a saline spray or flush. Over-the-counter saltwater sprays make your nostrils moist, which makes it easier to blow your nose. You may also want to try nasal irrigation. renova
What Are the Symptoms of HSV? Acyclovir is used to treat infections caused by herpes viruses. Illnesses caused by herpes viruses include genital herpes, cold sores, shingles, and chicken pox. If you have sores, wear loose-fitting clothing to keep from irritating them. This medication contains sodium. Be sure the area is completely clean and dry before putting on a fresh diaper. Serial analyses of the 3-month recurrence rates for the patients showed that 71% to 87% were recurrence free in each quarter. This medication may also help reduce how long pain remains after the sores heal. In addition, in people with a weakened immune system, acyclovir can decrease the risk of the virus spreading to other parts of the body and causing serious infections. ipan.info toprol
Zovirax is available in generic form. Like seasonal flu, pandemic swine flu can cause neurologic symptoms in children. These events are rare, but, as cases associated with seasonal flu have shown, they can be very severe and often fatal. Symptoms include or changes in mental status confusion or sudden cognitive or behavioral changes. If soap and water are not available, with an alcohol-based hand gel. Rub your hands together until the alcohol dries completely. Special Senses: Visual abnormalities. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 'Multum' is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Carcinogenesis, Mutagenesis, Impairment of Fertility: Systemic exposure following topical administration of acyclovir is minimal. Dermal carcinogenicity studies were not conducted. Results from the studies of carcinogenesis, mutagenesis, and fertility are not included in the full prescribing information for Zovirax Ointment 5% due to the minimal exposures of acyclovir that result from dermal application. Information on these studies is available in the full prescribing information for ZOVIRAX Capsules, Tablets, and Suspension and ZOVIRAX for Injection. Zovirax tablets are available in 200, 400 and 800 mg strengths and as a liquid suspension with 200 mg strength per 5 ml. Usual doses are 800 mg every 4 hours, 5 times a day for 10 days for shingles; doses for genital herpes infection are the same interval but start with 200 mg. Doses for chickenpox is the same as shingles except it goes for only 5 days for adults; for children ages 2 and up are weight based 20 mg per Kg up to 40 Kg, 5 times a day for 5 days. Over 40 Kg, the person gets the adult dose for 5 days. Zovirax may interact with probenecid. Tell your doctor all medications and supplements you use. There are no good studies on pregnant women. Zovirax may be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution is advised with use of Zovirax in women who are breastfeeding since the drug is secreted in breast milk. Safety and efficacy has not been studied in pediatric patients below the age of 2 years. Store at room temperature away from moisture and heat. What happens if I miss a dose? Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Zinc oxide topical cream may reduce the duration of an outbreak. Lynparza olaparib belongs to a new class of drugs called poly ADP-ribose polymerase PARP inhibitors. The drug is for women who have already received extensive treatment for advanced associated with defective BRCA genes, according to an FDA news release issued Friday. Pregnant women have been particularly vulnerable to severe flu and death. The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. How should I take acyclovir Zovirax? In clinical trials of initial genital herpes infections, Zovirax Ointment 5% has shown a decrease in healing time and, in some cases, a decrease in duration of viral shedding and duration of pain. In studies in immunocompromised patients primarily with herpes labialis, there was a decrease in duration of viral shedding and a slight decrease in duration of pain. price of disulfiram 100mg
Chickenpox: Chickenpox in otherwise healthy children is usually a self-limited disease of mild to moderate severity. Adolescents and adults tend to have more severe disease. Do not consider Communities as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. Do you think there is a chance this will go away? Reference Listed Drug RLD is an approved drug product to which new generic versions are compared to show that they are bioequivalent. A drug company seeking approval to market a generic equivalent must refer to the Reference Listed Drug in its Abbreviated New Drug Application ANDA. By designating a single reference listed drug as the standard to which all generic versions must be shown to be bioequivalent, FDA hopes to avoid possible significant variations among generic drugs and their brand name counterpart. Place it in your hand, then apply it to the diaper area. Antiviral Activities: The quantitative relationship between the in vitro susceptibility of herpes viruses to antivirals and the clinical response to therapy has not been established in humans, and virus sensitivity testing has not been standardized. Sensitivity testing results, expressed as the concentration of drug required to inhibit by 50% the growth of virus in cell culture IC 50 vary greatly depending upon a number of factors. Drink up. Getting plenty of fluids thins your mucus and breaks up congestion. It also prevents the headaches and fatigue that dehydration causes. Keep a glass or reusable bottle on hand, and refill it with water. Skip caffeinated sodas, coffee, and alcohol, which can dry you out. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 'Multum' is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. How should I use Zovirax Topical acyclovir topical? HSV that causes them. Most will go away on their own. But medicines may slightly reduce the duration of cold sores and sometimes prevent a future outbreak. This medication passes into breast milk. Consult your doctor before breast-feeding. endep
ZOVIRAX acyclovir Ointment 5% is indicated in the management of initial genital herpes and in limited nonlifethreatening mucocutaneous HSV infections in immunocompromised patients. Urogenital: Renal failure, renal pain may be associated with renal failure elevated blood urea nitrogen, elevated creatinine, hematuria see WARNINGS. Continue to take this medication until the full prescribed amount is finished. Do not change your dose, skip any doses, or stop this medication early without your doctor's approval. Pediatric Use: Safety and effectiveness in pediatric patients have not been established. By then, many people either already had the flu or figured the danger had passed. It shortens the duration and size of the cold sore in its tracks. From my experience, it's important to begin applying it immediately for best results. If you wait until the cold sore is large, it's far less effective. If you get it early, it stops growing and hence less blister and scabbing. I get a cold sore around once or twice a year, usually stress or weather induced. Abbreva has been really effective for me, and nothing else ever was. Use it frequently in the beginning, but be cautious because i think it has mild side effects like nauseau and insomnia if you use too much - ymmv. American Academy of Otolaryngology -- Head and Neck Surgery: “Antihistamines, Decongestants, and Cold Remedies. HSV-1 2 HSV-2 and -zoster virus VZV. Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Zovirax. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication. It can speed up healing of the sores and decrease symptoms such as tingling, pain, burning, . belongs to a class of known as antivirals. It works by stopping the growth of the virus. Avoid close contact -- that is, being within 6 feet -- with people who have flu-like symptoms. Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the outbreak. Store at room temperature between 59-77 degrees F 15-25 degrees C away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
This results in a 60% decrease in plasma concentrations following a 6-hour dialysis period. There's a difference between a face mask and a respirator. A face mask does not seal tightly to the face. Face masks include masks labeled as surgical, dental, medical procedure, isolation, or laser masks. Respirators are N95- or higher-rated filtering face pieces that fit snugly to the face. Respirators filter out virus particles when correctly adjusted -- which is not as simple as it sounds. Our Zovirax Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. DNA polymerase. Clinical isolates of HSV and VZV with reduced susceptibility to acyclovir have been recovered from immunocompromised patients, especially with advanced HIV infection. While most of the acyclovir-resistant mutants isolated thus far from immunocompromised patients have been found to be TK-deficient mutants, other mutants involving the viral TK gene TK partial and TK altered and DNA polymerase have been isolated. TK-negative mutants may cause severe disease in infants and immunocompromised adults. The possibility of viral resistance to acyclovir should be considered in patients who show poor clinical response during therapy. prinivil in uae
These medicines have little effect after the sore develops. Patients should be advised to maintain adequate hydration. Take an over-the-counter remedy. You may find relief with one of these medications. Initial Genital Herpes: Double-blind, placebo-controlled studies have demonstrated that orally administered Zovirax significantly reduced the duration of acute infection and duration of lesion healing. The duration of pain and new lesion formation was decreased in some patient groups. H1N1 swine flu virus apparently spreads just like regular flu. You could pick up germs directly from airborne droplets from the cough or sneeze of an infected person. Do not stop taking any medications without consulting your healthcare provider. But the CDC strongly recommends antiviral treatment for people at risk of severe flu complications who come down with flu-like symptoms. Since it's very important to start these drugs soon after symptoms appear, doctors should offer treatment to at-risk patients if they suspect they have the flu. Doctors should not rely on rapid flu tests they are too unreliable for definitive diagnosis or wait for results of lab-based tests because they take too long. But you can find relief faster with these smart moves. As we're all in this together, nobody will be asked to provide proof of citizenship or legal immigration. Continued Can I still eat pork? Do not share this medication with others. However, tinnitus that is caused by middle ear issues like fluid may just go away in time. At this point, there is really nothing that can be done that would influence outcome. cardizem purchase shopping canada
No. Rare vaccine reactions do happen, even with the seasonal flu vaccine. But flu experts at the National Institutes of Health, the CDC, and the FDA note that getting the flu is far more risky than getting the vaccine. This drug may rarely make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. General: Fever, headache, pain and peripheral edema. Can tinnitus be a side effect of this med after 4 years? Apply only enough cream to cover the cold sore or tingly area. Rub in gently until the cream disappears. Acyclovir topical cream may be applied 5 times daily for 4 days. Follow your doctor's instructions. Properly discard this product when it is expired or no longer needed. Consult your or local waste disposal company. No matter how careful you are, your little one will probably get at some point. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. This medication is also used to treat outbreaks of genital herpes. In people with frequent outbreaks, acyclovir is used to help reduce the number of future episodes. Adults With Impaired Renal Function: The half-life and total body clearance of acyclovir are dependent on renal function. A dosage adjustment is recommended for patients with reduced renal function see DOSAGE AND ADMINISTRATION. To reduce the risk of spreading genital herpes to others, stop all sexual activity during an outbreak until it is completely healed. Many people who have died of H1N1 swine flu had bacterial co-infections, particularly pneumococcal infections. There's a against pneumococcal infections. It's routine for children and recommended for adults with underlying health conditions, smokers, or people over age 65. If your flu symptoms get worse after getting better, call your doctor. You may need treatment with antibiotic medications. In studies of recurrent genital herpes and of herpes labialis in nonimmunocompromised patients, there was no evidence of clinical benefit; there was some decrease in duration of viral shedding. That's not easy to do, so keep those hands clean. Hepatobiliary Tract and Pancreas: Elevated liver function tests, hepatitis, hyperbilirubinemia, jaundice. where can i get phenazopyridine in canada
Withdrawal of Cold Medicines. Acyclovir does not protect against the spread of genital herpes. To lower the chance of giving herpes to your partner, do not have sexual contact during an outbreak or if you have symptoms. You can spread genital herpes even if you do not have symptoms. Zovirax Capsules, Tablets, and Suspension may be administered with or without food. Sensitivity testing results, expressed as the concentration of drug required to inhibit by 50% the growth of virus in cell culture IC 50 vary greatly depending upon a number of factors. Like seasonal flu, children who get swine flu can have serious neurological complications such as seizures and Reye's syndrome. But as with seasonal flu, these complications fortunately are rare. This medication works best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals. Zovirax Ointment 5% is intended for cutaneous use only and should not be used in the eye. Intravenous Zovirax is indicated for the treatment of varicella-zoster infections in immunocompromised patients. So, plan ahead. Learn how to treat and prevent flare-ups. Your baby's little bottom will thank you! Ferret studies suggest that swine flu spreads less easily by small, airborne droplets than does seasonal flu. But it does spread by this route, and it may begin to spread even more readily as the new virus fully adapts to humans. Smooth on cream or ointment to your baby's clean, dry bottom before putting on a clean diaper. Look for zinc oxide or petrolatum petroleum jelly on the ingredients list. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, conditions related to a weakened immune system such as HIV disease, bone marrow transplant, kidney transplant. H1N1 virus has become a seasonal flu bug. Check your baby's diaper often, and change it as soon as it becomes wet or soiled. desloratadine
Take this medication by mouth with or without food, usually 2 to 5 times a day as directed by your doctor. Drink plenty of fluids while taking this medication unless your doctor directs you otherwise. Avoid getting this medication in your eyes, nose, or mouth. If this does happen, rinse with water. When treating a cold sore, apply the medication only the outer part of your lips. That will help prevent your flu from spreading. If you can do it comfortably, wear a surgical mask if you must be around others. Often, the appearance of herpes simplex virus is typical and no testing is needed to confirm the diagnosis. If a provider is uncertain, herpes simplex can be diagnosed with lab tests, including DNA -- or PCR -- tests and virus cultures. How Is Herpes Simplex Treated? Patent and Trademark Office and assigns exclusive legal right to the patent holder to protect the proprietary chemical formulation. The patent assigns exclusive legal right to the inventor or patent holder, and may include entities such as the drug brand name, trademark, product dosage form, ingredient formulation, or manufacturing process A patent usually expires 20 years from the date of filing, but can be variable based on many factors, including development of new formulations of the original chemical, and patent infringement litigation. Yes, there is always a chance that your tinnitus will self-resolve. Your ENT feels that it will, so keep hoping and praying in that direction. Mine, of course, did not go away. Perhaps, it was Nature's Way of making me more sympathetic on this ENT board! These antiviral medications aren't a question of life or death for the vast majority of people. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. H1N1 swine flu cases surged as schools opened in the fall. What is H1N1 swine flu?
Several treatments are available if you wish to try an alternative way to ease your symptoms. Thank you for your time. Nausea, diarrhea, headache, or vomiting may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Exposure does not guarantee infection or illness, so there's still a good chance you won't get the flu. Approval of the AstraZeneca drug was based on a of almost 140 women with BRCA mutation-associated ovarian cancer. Thirty-four percent of the patients on the drug had partial shrinkage or complete disappearance of their tumors for an average of eight months, the FDA reported. Only lab tests can definitively show whether you've got swine flu. State health departments can do these tests. H1N1 swine flu cases. It's possible some schools in your community may temporarily close, or even that major gatherings may be canceled. So make contingency plans just in case you are affected. Therefore, systemic absorption of acyclovir after topical application is minimal. Studies of the swine flu virus show that it is more infectious to lung cells than are seasonal flu viruses. But studies also suggest that the swine flu virus is less well adapted to humans and may be harder to inhale deep into the lungs. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. How long does the flu virus survive on surfaces? Often, the appearance of HSV is typical and no testing is needed to confirm the diagnosis. If a provider is uncertain, HSV can be diagnosed with laboratory tests, including DNA tests and virus cultures. How Is Herpes Treated? order prednisone online
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There may be other drugs that can affect acyclovir. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Acyclovir will not prevent the spread of genital herpes. Avoid sexual intercourse or use a latex condom to prevent spreading the virus to others. To distinguish it from flu viruses that infect mainly pigs and from the seasonal A H1N1 viruses that have been in circulation for many years, the CDC calls the virus "2009 H1N1 virus.
You should not use this medicine if you are allergic to acyclovir or valacyclovir Valtrex. Exclusivity is the sole marketing rights granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent. Exclusivity periods can run from 180 days to seven years depending upon the circumstance of the exclusivity grant. Zovirax is contraindicated for patients who develop hypersensitivity to acyclovir or valacyclovir.
Wear a glove or a finger cot or use a cotton swab when applying acyclovir topical ointment to avoid spreading the virus to other body parts and to other people. Treatment with acyclovir topical should be started as soon as possible after the first appearance of symptoms such as tingling, burning, blisters. Pregnancy: Teratogenic Effects: Acyclovir was not teratogenic in the mouse, rabbit, or rat at exposures greatly in excess of human exposure. There are no adequate and well-controlled studies of systemic acyclovir in pregnant women. A prospective epidemiologic registry of acyclovir use during pregnancy was established in 1984 and completed in April 1999. There were 749 pregnancies followed in women exposed to systemic acyclovir during the first trimester of pregnancy resulting in 756 outcomes. The occurrence rate of birth defects approximates that found in the general population. However, the small size of the registry is insufficient to evaluate the risk for less common defects or to permit reliable or definitive conclusions regarding the safety of acyclovir in pregnant women and their developing fetuses. Systemic acyclovir should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Hallucinations, psychosis, confusion, aggressive behavior, agitation may be more marked in older adults and those with renal impairment. In general, a person can only get HSV-2 infection during sexual contact with someone who has a genital HSV-2 infection. Both HSV-1 and HSV-2 can be spread even if sores are not present. F in a dry place. When should I see my doctor?